Sfrp2 - secreted frizzled-related protein 2

Predicted to enable several functions, including Wnt-protein binding activity; fibronectin binding activity; and signaling receptor binding activity. Involved in negative regulation of canonical Wnt signaling pathway; positive regulation of canonical Wnt signaling pathway; and response to nutrient. Predicted to be located in collagen-containing extracellular matrix. Predicted to be active in extracellular space. Biomarker of myocardial infarction. Orthologous to human SFRP2 (secreted frizzled related protein 2). [provided by Alliance of Genome Resources, Apr 2022]