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中文人类
ACACA - Acetyl-CoA Carboxylase Alpha
Alias:
ACC
ACAC
ACC1
ACCA
Acac1
hACC1
ACACAD
ACCalpha
ACACalpha
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乙酰辅酶A羧化酶（ACC）是一种复杂的多功能酶系统。ACC是一种含有生物素的酶，催化乙酰辅酶A的羧基化作用，生成丙二酰辅酶A，这是脂肪酸合成中的限速步骤。ACC有两种形式，α和β，由两种不同的基因编码。ACC-α在脂肪生成组织中高度丰富。该酶在转录和翻译水平上受到长期控制，并通过靶定的丝氨酸残基的磷酸化/脱磷酸化和通过柠檬酸或棕榈酰辅酶A的变构转化受到短期调节。已经发现这个基因有多个可变剪接转录变异体，在5’序列上不同并编码不同的异构体。[RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ACACA Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
