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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
RT1-CE5 - RT1 class I, locus CE5
Alias:
RT1-E2
rt1-El
RT1-CE7
RT1-C/E5
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测具有多种功能,包括14-3-3蛋白结合活性;TAP结合活性;和β-2-微球蛋白结合活性。参与多种过程,包括通过ER途径,TAP非依赖性的内源肽抗原通过MHC I类抗原的处理和呈递;内源肽抗原通过MHC Ib类的处理和呈递;以及调节淋巴细胞介导的免疫。位于几种细胞组件中,包括细胞器的边界膜;细胞表面;和高尔基体。是MHC Ib类蛋白复合物的一部分。在质膜的外侧和细胞外空间中活性。该基因的拟人物种参与了多种疾病,包括哮喘(多种);自身免疫性疾病(多种);眼疾(多种);人类免疫缺陷病毒感染性疾病(多种);和内耳疾病(多种)。与几种人类基因包括HLA-F(主要组织相容性复合体I类F)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:309607
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
309607
20
8
76059 bp
Unknown
24
5
RT1-CE5 Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Abundance
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Cell-specific RNA expression
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Type
Name
MGI
Strain of Origin
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Mutations
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References Literature
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PMID
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Year
IF
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