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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Pik3cg - phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma
Alias:
PI3Kgamma
p110gamma
p120-PI3K
5830428L06Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活1-磷酸肌醇-3-激酶活性。参与几个过程,包括磷酸肌醇3-激酶信号传导;Rac蛋白信号传导的正调控;和鞘氨醇-1-磷酸受体信号通路。在几个过程的上游或内部发挥作用,包括细胞对cAMP的反应;成纤维细胞凋亡过程的负调控;和钙离子跨膜运输的调节。预测位于细胞质中。预测是磷脂酰肌醇3-激酶复合物,类IA和磷脂酰肌醇3-激酶复合物,类IB的一部分。预测在细胞质和质膜中是活跃的。在血细胞同源系统和胸腺原基中表达。这个基因的人类同源物与自闭症和猪流感有关。与人类PIK3CG(磷脂酰肌醇-4,5-二磷酸3-激酶催化亚单位γ)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:30955
ENSEMBL:ENSMUSG00000020573
UNIPROT:Q9JHG7
Basic Information
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Length
MW (kDa)
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30955
6
11
35548 bp
126.40
12
21
Pik3cg Genetics information (-)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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