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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Bin1 - bridging integrator 1
Alias:
ALP-1
Amphl
SH3P9
BRAMP-2
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有天冬氨酸型内肽酶抑制活性,并参与包括负调控淀粉样前体蛋白分解代谢过程、负调控阳离子跨膜运输以及调控心脏收缩等多个过程。在肌肉细胞分化的上游或内部发挥作用。位于几个细胞组件中,包括T-管、树突和核膜。在几个结构中表达,包括中枢神经系统、胚胎间充质、眼睛、心脏和肌肉组织。该基因的人类同源物与乳腺癌、核周围性肌病2和前列腺腺癌有关。与人类BIN1(桥接整合子1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:30948
ENSEMBL:ENSMUSG00000024381
UNIPROT:O08539
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
30948
26
19
59123 bp
64.47
8
15
Bin1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Type
Name
MGI
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