大鼠

Irag1 - inositol 1,4,5-triphosphate receptor associated 1

Alias:
Mrvi1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因与一个假定的鼠肿瘤抑制基因相似,该基因通常被鼠艾滋病相关病毒(MRV)破坏。 在内质网膜上发现的编码蛋白质与Jaw1相似,Jaw1是一种在淋巴样分化过程中表达受到抑制的淋巴限制蛋白。 研究表明,MRV在同源鼠基因处的整合通过改变髓样细胞生长和/或分化的重要基因的表达,诱发髓样白血病。 因此,这个基因可能作为髓样白血病肿瘤抑制基因发挥作用。 已经发现了这个基因的可变剪接转录变异体。 [RefSeq,2013年11月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
5
21
112517 bp
Unknown
5
3

Irag1 Genetics information (-)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
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Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
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