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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Blm - BLM RecQ like helicase
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有预测的多种功能,包括ATP结合活性;DNA结合活性;和DNA解旋酶活性。参与多个过程,包括DNA几何变化;DNA代谢过程;和细胞大分子生物合成过程的调控。在几个过程中起上游或内部作用,包括胸腺细胞的负向调控;DNA重组的调控;和通过姐妹染色单体交换的复制出生的双链断裂修复。位于细胞质;核;和复制叉。是蛋白质复合物的一部分。在染色体;细胞质;和核中活跃。与PML体和染色体,端粒区域共定位。该基因的人类同源物与Bloom综合征有关。与人类BLM(RecQ样解旋酶)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:308755
ENSEMBL:ENSRNOG00000011213
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
308755
4
23
86242 bp
Unknown
13
--
Blm Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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MGI
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