人类

NRG1 - Neuregulin 1

Alias:
GGF
HGL
HRG
NDF
ARIA
GGF2
HRG1
HRGA
SMDF
MST131
MSTP131
NRG1-IT2
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是一种膜糖蛋白,可以传递细胞间信号,并在多个器官系统的生长和发育中扮演关键角色。通过使用替代启动子和剪接,从这个基因中产生了大量不同的异构体。这些异构体以组织特异性的方式表达,并在其结构上存在显著差异,被归类为I型、II型、III型、IV型、V型和VI型。这个基因的调控异常与癌症、精神分裂症和双相情感障碍(BPD)等疾病有关。[RefSeq,2016年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
28
12
1134802 bp
70.39
41
1
23
21

NRG1 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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