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中文人类
ERVW-1 - Endogenous Retrovirus Group W Member 1, Envelope
Alias:
ENV
ENVW
HERVW
ERVWE1
HERV7Q
HERV-7q
HERVWENV
HERV-W-ENV
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人类内源性逆转录病毒（HERV）家族在正常胎盘组织中高表达，提示HERV在生殖功能中具有重要作用。该基因位于第7染色体上的HERV原病毒上，其gag和pol基因具有失活突变。该基因编码包膜糖蛋白基因，似乎得到了选择性保留。该基因的蛋白质产物在胎盘合胞滋养层中表达，并参与合胞滋养层细胞融合以形成胎盘的合胞层。该蛋白质具有典型的逆转录病毒包膜蛋白质的特征，包括分离表面（SU）和跨膜（TM）蛋白质的纤蛋白切割位点，这些蛋白质形成异源二聚体。已发现该基因的编码相同蛋白质的可变剪接转录变异体。[RefSeq，2010年3月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
ERVW-1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
