Csf1r - colony stimulating factor 1 receptor

Predicted to enable several functions, including macrophage colony-stimulating factor receptor activity; protein homodimerization activity; and protein phosphatase binding activity. Involved in several processes, including nervous system development; positive regulation of osteoclast differentiation; and regulation of bone resorption. Predicted to be located in cell surface; nucleoplasm; and plasma membrane. Predicted to be part of CSF1-CSF1R complex and receptor complex. Predicted to be integral component of plasma membrane. Used to study anti-basement membrane glomerulonephritis; bone development disease; infertility; and lymphopenia. Human ortholog(s) of this gene implicated in adult-onset leukoencephalopathy with axonal spheroids and pigmented glia and renal cell carcinoma. Orthologous to human CSF1R (colony stimulating factor 1 receptor). [provided by Alliance of Genome Resources, Apr 2022]