Sirt5 - sirtuin 5

Predicted to enable NAD+ binding activity; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides; and zinc ion binding activity. Involved in negative regulation of cardiac muscle cell apoptotic process and response to nutrient levels. Predicted to be located in mitochondrial inner membrane; mitochondrial intermembrane space; and mitochondrial matrix. Predicted to be active in cytosol and mitochondrion. Orthologous to human SIRT5 (sirtuin 5). [provided by Alliance of Genome Resources, Apr 2022]