S1pr3 - sphingosine-1-phosphate receptor 3

Predicted to enable G protein-coupled receptor activity and integrin binding activity. Predicted to be involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; negative regulation of establishment of endothelial barrier; and regulation of metabolic process. Predicted to act upstream of or within several processes, including Notch signaling pathway; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; and regulation of interleukin-1 beta production. Predicted to be integral component of membrane. Predicted to be active in cytoplasm and plasma membrane. Orthologous to human S1PR3 (sphingosine-1-phosphate receptor 3). [provided by Alliance of Genome Resources, Apr 2022]