Predicted to enable serine-type endopeptidase activity. Involved in blood coagulation. Located in extracellular space. Used to study hyperhomocysteinemia. Human ortholog(s) of this gene implicated in angioedema (multiple); cerebrovascular disease (multiple); factor XII deficiency; and myocardial infarction. Orthologous to human F12 (coagulation factor XII). [provided by Alliance of Genome Resources, Apr 2022]