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中文人类
HDAC2 - Histone Deacetylase 2
Alias:
HD2
RPD3
YAF1
KDAC2
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这个基因产物属于组蛋白去乙酰化酶家族。组蛋白去乙酰酶通过形成大型多蛋白复合体来发挥作用，负责核心组蛋白（H2A、H2B、H3和H4）N端区域的赖氨酸残基的去乙酰化。这种蛋白质通过与包括YY1（一种哺乳动物锌指转录因子）在内的多种蛋白质结合，形成转录抑制复合物。因此，它在转录调控、细胞周期进展和发育事件中发挥着重要作用。可变剪接导致多个转录变异体。[RefSeq，2010年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
HDAC2 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
