人类

HCK - HCK Proto-oncogene, Src Family Tyrosine Kinase

Alias:
JTK9
AIPCV
p59Hck
p61Hck
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是Src家族酪氨酸激酶成员。这种蛋白质主要在造血细胞中表达,特别是在髓系和B淋巴细胞谱系的细胞中。它可能有助于将Fc受体与呼吸爆发的激活耦合。此外,它可能在中性粒细胞的迁移和中性粒细胞的脱颗粒中发挥作用。由于选择性剪接和替代翻译起始密码子的使用,产生了具有不同亚细胞分布的多种异构体,包括非AUG (CUG) 密码子。[由RefSeq,2010年2月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
6
13
49615 bp
59.60
26
1
7
55

HCK Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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