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中文人类
SERPIND1 - Serpin Family D Member 1
Alias:
HC2
LS2
HCF2
HCII
HLS2
THPH10
D22S673
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这个基因属于丝氨酸蛋白酶抑制因子基因超家族。丝氨酸蛋白酶抑制因子在许多过程中发挥作用，包括炎症、凝血和癌症转移。这个家族的成员具有高度保守的二级结构，具有一个与蛋白酶活性部位相互作用的活性中心环，以抑制蛋白酶活性。这个基因编码一种作为凝血酶和胰凝乳蛋白酶抑制剂的血浆丝氨酸蛋白酶。该蛋白由肝素、皮肤素硫酸盐和糖胺聚糖激活。这个基因的等位基因变异与肝素辅因子II缺乏症有关。[RefSeq，2015年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
SERPIND1 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
