Adamts5 - ADAM metallopeptidase with thrombospondin type 1 motif, 5

Predicted to enable extracellular matrix binding activity; heparin binding activity; and metalloendopeptidase activity. Involved in tooth eruption. Predicted to be located in extracellular space. Predicted to be active in extracellular matrix. Used to study osteoarthritis. Biomarker of degenerative disc disease; mucopolysaccharidosis VI; and osteoarthritis. Human ortholog(s) of this gene implicated in osteoarthritis. Orthologous to human ADAMTS5 (ADAM metallopeptidase with thrombospondin type 1 motif 5). [provided by Alliance of Genome Resources, Apr 2022]