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中文人类
H2AZ1 - H2A.Z Variant Histone 1
Alias:
H2AZ
H2A.z
H2A/z
H2AFZ
H2A.Z-1
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组蛋白是负责真核生物染色体纤维核小体结构的基本核蛋白质。核小体由大约146bp的DNA围绕一个由四对核心组蛋白（H2A、H2B、H3和H4）组成的组蛋白八聚体组成。通过连接蛋白组蛋白H1与核小间DNA的相互作用，染色质纤维进一步压缩，形成更高阶的染色质结构。这个基因编码一个与家族其他成员不同的、独立于复制的组蛋白H2A家族成员。研究表明，这种特定的组蛋白在胚胎发育中是必需的，缺乏功能的组蛋白H2A导致胚胎致死。[RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
H2AZ1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
