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Lrrk2 - leucine-rich repeat kinase 2

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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能实现几个功能,包括GTP结合活性;细胞骨架蛋白结合活性;和蛋白质丝氨酸/苏氨酸激酶活性。参与几个过程,包括神经系统发育;宏分子代谢过程的正向调节;和微小胶质细胞激活的正向调节。位于几个细胞成分中,包括轴突;树突;和胞质团。用于研究神经退行性疾病。糖尿病神经病变的生物标志物。这个基因的人类同源物涉及克罗恩病;帕金森病;帕金森病8;帕金森氏病;和癌症。与人类LRRK2(富亮氨酸重复序列激酶2)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
5
51
161016 bp
Unknown
30
--

Lrrk2 Genetics information (+)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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