Celsr1 - cadherin, EGF LAG seven-pass G-type receptor 1

Predicted to enable G protein-coupled receptor activity and calcium ion binding activity. Predicted to be involved in cell-cell adhesion and establishment of planar polarity. Predicted to act upstream of or within several processes, including Rho protein signal transduction; apical protein localization; and morphogenesis of an epithelium. Predicted to be located in nucleoplasm and plasma membrane. Human ortholog(s) of this gene implicated in hereditary lymphedema. Orthologous to human CELSR1 (cadherin EGF LAG seven-pass G-type receptor 1). [provided by Alliance of Genome Resources, Apr 2022]