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中文人类
GZMH - Granzyme H
Alias:
CCP-X
CGL-2
CSP-C
CTLA1
CTSGL2
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这个基因编码丝氨酸蛋白酶肽酶S1家族的成员。可变剪接产生多种转录子变异体，其中至少一个编码前原蛋白，该前原蛋白在蛋白水解过程中被加工成天冬氨酸蛋白酶样蛋白酶。据报道，这种蛋白质在免疫系统的NK（自然杀手）细胞中组成性表达，并通过诱导目标细胞死亡和直接在病原体感染的细胞中切割底物，可能在先天免疫反应的细胞毒性臂中发挥作用。这个基因位于染色体14上的另一个颗粒酶亚家族成员的基因簇中。[RefSeq, Nov 2015提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
GZMH Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
