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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
UBQLN2 - Ubiquilin 2
Alias:
DSK2
ALS15
CHAP1
N4BP4
PLIC2
HRIHFB2157
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个类似于泛素蛋白(泛素样蛋白),与酵母、大鼠和青蛙中的相关产物具有高度相似性。泛素样蛋白包含一个N-端泛素样结构域和一个C-端泛素相关结构域。它们与蛋白酶体和泛素连接酶物理结合;因此,被认为在功能上将泛素化机制连接到蛋白酶体,以影响体内蛋白质的降解。这种泛素样蛋白还被证明可以结合Hsp70样Stch蛋白的ATP酶结构域。[由RefSeq,2009年10月提供]
Related ID:
NCBI:29978
ENSEMBL:ENSG00000188021
HGNC:12509
UNIPROT:Q9UHD9
OMIM:300264
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
29978
1
1
4242 bp
65.70
136
3
3
29
UBQLN2 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Mutations
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Transcripts & Proteins
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Transcript
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Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Name
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Status
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Link
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References Literature
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No Data Found!
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