人类

UBQLN2 - Ubiquilin 2

Alias:
DSK2
ALS15
CHAP1
N4BP4
PLIC2
HRIHFB2157
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个类似于泛素蛋白(泛素样蛋白),与酵母、大鼠和青蛙中的相关产物具有高度相似性。泛素样蛋白包含一个N-端泛素样结构域和一个C-端泛素相关结构域。它们与蛋白酶体和泛素连接酶物理结合;因此,被认为在功能上将泛素化机制连接到蛋白酶体,以影响体内蛋白质的降解。这种泛素样蛋白还被证明可以结合Hsp70样Stch蛋白的ATP酶结构域。[由RefSeq,2009年10月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
1
4242 bp
65.70
136
3
3
29

UBQLN2 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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