人类

A1CF - APOBEC1 Complementation Factor

Alias:
ACF
ASP
ACF64
ACF65
APOBEC1CF
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
哺乳动物载脂蛋白B mRNA在特定位点经历C到U的脱氨基作用,这由一个包含最小核心的多元酶复合物介导,该核心由APOBEC-1和这个基因编码的补充因子组成。这个基因产物具有三个不同的RNA识别基序,并属于hnRNP R家族的RNA结合蛋白。已经提出,这个补充因子作为RNA结合亚基,将APOBEC-1与上游的胞嘧啶脱氨基作用进行对接。研究表明,这个蛋白也可能涉及其他RNA编辑或RNA处理事件。已经发现这个基因的几个不同转录变异体,编码几个不同的异构体。[RefSeq,2010年11月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
14
13
86219 bp
65.20
22
--
7
13

A1CF Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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