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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
MDFIC - MyoD Family Inhibitor Domain Containing
Alias:
HIC
MDFIC1
LMPHM12
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这种基因产物是一个蛋白质家族的成员,其特征是具有一个特定的富含半胱氨酸的C端结构域,参与病毒基因组表达的转录调控。从上游的非AUG (GUG) 起始密码子和框内的下游AUG密码子进行可选的翻译起始,产生两种不同的亚型,分别是p40和p32,它们具有不同的亚细胞定位;p32主要存在于细胞质中,而p40定位到核仁。两种亚型都具有转录调控活性,这是由富含半胱氨酸的C端结构域所决定的。可选的剪接导致多种转录变异体。[由RefSeq,2009年10月提供]
Related ID:
NCBI:29969
ENSEMBL:ENSG00000135272
HGNC:28870
UNIPROT:Q9P1T7
OMIM:614511
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
29969
3
5
97824 bp
25.79
29
1
4
9
MDFIC Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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Transcripts & Proteins
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Transcript
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Protein
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Name
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Status
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Link
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References Literature
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