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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
ANAPC4 - Anaphase Promoting Complex Subunit 4
Alias:
APC4
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
一个大型的被称为促减数复合物(APC)或细胞周期素的蛋白复合物,通过将特定的底物如细胞周期素和减数抑制剂泛素化,从而促进有丝分裂中期到后期过渡,这些底物随后被26S蛋白酶体降解。生物化学研究表明,从酵母到人,脊椎动物的APC含有8个亚基,其组成在生物中高度保守。这个基因产品的确切功能尚不清楚。已经发现这个基因有两个编码不同异型的转录变异体。[RefSeq,2013年11月提供]
Related ID:
NCBI:29945
ENSEMBL:ENSG00000053900
HGNC:19990
UNIPROT:Q9UJX5
OMIM:606947
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
29945
5
29
41236 bp
92.12
21
--
3
18
ANAPC4 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
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Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
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Journal
Year
IF
No Data Found!
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