人类

ANAPC2 - Anaphase Promoting Complex Subunit 2

Alias:
APC2
Favorite
Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
一个大型的被称为促减数复合物(APC)或细胞周期素的细胞质体的蛋白质复合体,通过将特定的底物如细胞周期素和减数抑制剂进行泛素化,从而促进有丝分裂中期到减数期的过渡。这些底物随后被26S蛋白酶体降解。生物化学研究表明,从酵母到人类的生物中,APC含有八个亚基,其组成高度保守。该基因的产物是复合物的组成部分,并与最近识别的一类被称为泛素的蛋白质具有序列相似性,这些蛋白质也可能涉及泛素介导的降解。[RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4
13
13777 bp
93.83
25
--
5
21

ANAPC2 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Mutation Direct
Sequence
Comparison
Al agent
Tutorials
Back to top