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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Iqgap1 - IQ motif containing GTPase activating protein 1
Alias:
mKIAA0051
D7Ertd237e
D7Ertd257e
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活小型GTP酶结合活性。参与细胞对生长因子刺激的响应;正调控蛋白激酶活性;和跨膜受体蛋白酪氨酸激酶信号通路。在成纤维细胞迁移的上游或内部发挥作用;负调控脱磷酸化;并调控细胞因子的产生。位于几个细胞组件中,包括皮质肌动蛋白细胞骨架;粘附斑;和侧向质膜。是核糖核酸蛋白复合物的一部分。在几个结构中表达,包括消化系统;中枢神经系统;早期概念期;生殖泌尿系统;和皮肤。与人类的正交基因IQGAP1(含IQ基序的GTP酶激活蛋白1)相同。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:29875
ENSEMBL:ENSMUSG00000030536
UNIPROT:Q9JKF1
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
29875
1
38
91958 bp
188.74
6
15
Iqgap1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Type
Name
MGI
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References Literature
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IF
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