Dguok - deoxyguanosine kinase

Predicted to enable deoxyadenosine kinase activity and deoxyguanosine kinase activity. Involved in ATP biosynthetic process; mitochondrial ATP synthesis coupled electron transport; and negative regulation of neuron projection development. Predicted to be active in cytosol and mitochondrion. Used to study mitochondrial DNA depletion syndrome 3. Human ortholog(s) of this gene implicated in autosomal recessive progressive external ophthalmoplegia with mitochondrial DNA deletions 4; mitochondrial DNA depletion syndrome 3; mitochondrial metabolism disease; and portal hypertension. Orthologous to human DGUOK (deoxyguanosine kinase). [provided by Alliance of Genome Resources, Apr 2022]