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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Apbb1 - amyloid beta precursor protein binding family B member 1
Alias:
FE65
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个具有DNA结合活性的转录因子,可以结合淀粉样蛋白-β和tau蛋白。它参与多种过程,包括组蛋白H4的乙酰化,负调控细胞周期G1/S期转换,以及调控核碱基化合物的代谢过程。该基因位于轴突、树突棘和突触膜等细胞组分中,并构成蛋白质复合物的一部分。它在突触前体中具有活性。人类该基因的同源物与阿尔茨海默病有关。该基因与人类APBB1(淀粉样前体蛋白结合家族B成员1)具有同源性。
Related ID:
NCBI:29722
ENSEMBL:ENSRNOG00000018020
UNIPROT:P46933
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
29722
9
14
23617 bp
77.66
6
6
Apbb1 Genetics information (-)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
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Type
Name
MGI
Strain of Origin
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