Gabra5 - gamma-aminobutyric acid type A receptor subunit alpha 5

Enables GABA receptor binding activity; GABA-A receptor activity; and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Involved in brain development and chemical synaptic transmission. Located in dendrite and neuronal cell body membrane. Part of receptor complex. Is active in GABA-ergic synapse. Is integral component of postsynaptic specialization membrane and integral component of presynaptic membrane. Human ortholog(s) of this gene implicated in bipolar disorder; developmental and epileptic encephalopathy 79; and mental depression. Orthologous to human GABRA5 (gamma-aminobutyric acid type A receptor subunit alpha5). [provided by Alliance of Genome Resources, Apr 2022]