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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Bmal1 - basic helix-loop-helix ARNT like 1
Alias:
Arntl
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质是一种与Clock形成异二聚体的基本螺旋-环-螺旋蛋白。这个异二聚体结合周期基因(Per1、Per2、Per3)和隐花色素基因(Cry1、Cry2)上游的E-box增强子元件,并激活这些基因的转录。Per和Cry蛋白通过与其在反馈环路中的Clock/Arntl复合物相互作用,实现异二聚化并抑制它们自己的转录。这个基因的缺陷与不育、糖异生和脂肪生成问题以及睡眠模式的改变有关。[由RefSeq,2014年1月提供]
Related ID:
NCBI:29657
ENSEMBL:ENSRNOG00000014448
UNIPROT:Q9EPW1
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
29657
12
21
98480 bp
68.62
21
7
Bmal1 Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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