Sp5 - Sp5 transcription factor

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to act upstream of or within bone morphogenesis; cellular response to organic cyclic compound; and post-anal tail morphogenesis. Orthologous to human SP5 (Sp5 transcription factor). [provided by Alliance of Genome Resources, Apr 2022]