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Adam10 - ADAM metallopeptidase domain 10

Alias:
MADM
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有金属内肽酶活性。参与几个过程,包括淀粉样蛋白-β的形成;树突状棘形态发生调控;以及对抗肿瘤药物的响应。位于几个细胞成分中,包括树突状棘;突触囊泡;和跨高尔基网络。在谷氨酸能突触和后突触中活跃。阿尔茨海默病的生物标志物;心肌病;白内障;癫痫状态;和胸主动脉瘤。这个基因的人类同源物与Kitamura网状痤疮有关。与人类ADAM10(金属肽酶结构域10)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
16
131882 bp
84.09
11
3

Adam10 Genetics information (+)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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