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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Adam10 - ADAM metallopeptidase domain 10
Alias:
MADM
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有金属内肽酶活性。参与几个过程,包括淀粉样蛋白-β的形成;树突状棘形态发生调控;以及对抗肿瘤药物的响应。位于几个细胞成分中,包括树突状棘;突触囊泡;和跨高尔基网络。在谷氨酸能突触和后突触中活跃。阿尔茨海默病的生物标志物;心肌病;白内障;癫痫状态;和胸主动脉瘤。这个基因的人类同源物与Kitamura网状痤疮有关。与人类ADAM10(金属肽酶结构域10)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:29650
ENSEMBL:ENSRNOG00000054257
UNIPROT:Q10743
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
29650
1
16
131882 bp
84.09
11
3
Adam10 Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Acting
Regulation
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Type
Name
MGI
Strain of Origin
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References Literature
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IF
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