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Htr2a - 5-hydroxytryptamine receptor 2A

Alias:
5Ht-2
5-HT2A
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
1-(4-碘-2,5-二甲氧基苯基)丙-2-胺结合活性;Gq/11耦合的5-羟色胺受体活性;5-羟色胺结合活性。参与几个过程,包括血管直径的维持;疼痛感觉的感知刺激检测;化学突触传递的调节。位于几个细胞成分中,包括细胞体纤维;树突杆;和神经元细胞体。在谷氨酸能突触中活跃。是突触后膜的集成组件和突触前膜的集成组件。用于研究充血性心力衰竭;高血糖;和胰腺炎。膀胱颈梗阻和精神分裂症的生物标志物。这个基因的人类同源物涉及几种疾病,包括酒精使用障碍;神经性厌食症;重度抑郁症;肥胖症;和强迫症。与人5-羟色胺受体2A(5-羟色胺受体2A)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
3
3
72154 bp
52.85
11
5

Htr2a Genetics information (+)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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