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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
GSTM5 - Glutathione S-transferase Mu 5
Alias:
GTM5
GSTM5-5
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
细胞质和膜结合形式的谷胱甘肽S-转移酶是由两个不同的超基因家族编码的。目前,已识别出八种不同的溶酶体细胞质哺乳动物谷胱甘肽S-转移酶:α、κ、μ、ω、π、σ、θ和ζ。本基因编码属于μ类的谷胱甘肽S-转移酶。μ类酶通过与谷胱甘肽结合,对包括致癌物、治疗药物、环境毒素和氧化应激产物在内的电化学化合物进行解毒作用。编码μ类酶的基因在1p13.3染色体上组织成一个基因簇,并且已知高度多态性。这些遗传变异可以改变个体对致癌物和毒素的易感性,以及影响某些药物的毒性及其疗效。在编码底物结合域的区域以及在组织表达模式中,这些基因的多样化已经发生,以适应越来越多的外来化合物。[由RefSeq提供,2008年7月]
Related ID:
NCBI:2949
ENSEMBL:ENSG00000134201
HGNC:4637
UNIPROT:P46439
OMIM:138385
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2949
3
8
6518 bp
25.68
13
--
9
5
GSTM5 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
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* This data comes from NCBI.
Gene Expression
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