Krt18 - keratin 18

Predicted to enable scaffold protein binding activity. Involved in several processes, including cholangiocyte apoptotic process; hepatocyte differentiation; and response to fructose. Located in several cellular components, including external side of plasma membrane; extracellular space; and keratin filament. Part of protein-containing complex. Biomarker of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis. Human ortholog(s) of this gene implicated in liver cirrhosis. Orthologous to human KRT18 (keratin 18). [provided by Alliance of Genome Resources, Apr 2022]