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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
大鼠
Mapt - microtubule-associated protein tau
Alias:
Tau
pTau
Mtapt
RNPTAU
MAPT_0N4R
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种功能,包括Hsp90蛋白结合活性;分子伴侣结合活性;以及酶结合活性。参与多种过程,包括氧化应激响应的内在凋亡信号通路;mRNA运输;以及长期突触抑制的正向调节。位于几个细胞组件中,包括轴突;质膜的细胞质侧;以及神经元细胞体。与微管蛋白共定位。用于研究脑疾病(多种);认知障碍(多种);肥胖症;以及tau病(多种)。作为中脑动脉梗死的生物标志物。这个基因的人类同源物涉及痴呆(多种);神经退行性疾病(多种);进行性核上麻痹;以及颞叶癫痫。正交人类MAPT(微管相关蛋白tau)。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:29477
ENSEMBL:ENSRNOG00000005133
UNIPROT:P19332
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
29477
33
10
97494 bp
Unknown
50
4
Mapt Genetics information (+)
mRatBN7.2
Sequence Homology
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* This data comes from NCBI.
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