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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
GSTM3 - Glutathione S-transferase Mu 3
Alias:
GST5
GSTB
GTM3
GSTM3-3
GSTM3TV2
hGSTM3-3
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
细胞质和膜结合形式的谷胱甘肽S-转移酶由两个不同的超基因家族编码。目前,已经确定了八种不同的可溶性细胞质哺乳动物谷胱甘肽S-转移酶类:α,κ,μ,ω,π,σ,θ和ζ。这个基因编码属于μ类的谷胱甘肽S-转移酶。μ类酶在通过与谷胱甘肽结合来解毒亲电化合物,包括致癌剂、治疗药物、环境毒素和氧化应激产物中发挥作用。编码μ类酶的基因在染色体1p13.3上的一个基因簇中组织起来,已知它们具有高度的多态性。这些遗传变异可以改变个体对致癌剂和毒素的易感性,以及影响某些药物的毒性和疗效。这个μ类基因的突变与癌症数量的小幅增加有关,可能是由于接触环境毒素所致。可变剪接导致多个转录变异体。[由RefSeq,2008年11月提供]
Related ID:
NCBI:2947
ENSEMBL:ENSG00000134202
HGNC:4635
UNIPROT:P21266
OMIM:138390
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
2947
1
9
7102 bp
26.56
6
1
4
9
GSTM3 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
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No data available
Transcripts & Proteins
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#
Transcript
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Type
Name
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Status
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References Literature
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