Nodal - nodal growth differentiation factor

Predicted to enable cytokine activity and type I activin receptor binding activity. Predicted to be involved in several processes, including positive regulation of macromolecule metabolic process; positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway; and transmembrane receptor protein serine/threonine kinase signaling pathway. Predicted to act upstream of or within several processes, including animal organ development; embryonic morphogenesis; and regulation of embryonic development. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in visceral heterotaxy. Orthologous to human NODAL (nodal growth differentiation factor). [provided by Alliance of Genome Resources, Apr 2022]