Nus1 - NUS1 dehydrodolichyl diphosphate synthase subunit

Predicted to contribute to dehydrodolichyl diphosphate synthase activity. Predicted to be involved in several processes, including dolichol biosynthetic process; dolichyl diphosphate biosynthetic process; and positive regulation of nitric-oxide synthase activity. Predicted to act upstream of or within cholesterol homeostasis; protein mannosylation; and regulation of intracellular cholesterol transport. Predicted to be located in membrane. Predicted to be part of dehydrodolichyl diphosphate synthase complex. Predicted to be active in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 55 and congenital disorder of glycosylation Iaa. Orthologous to human NUS1 (NUS1 dehydrodolichyl diphosphate synthase subunit). [provided by Alliance of Genome Resources, Apr 2022]