RT1-DMa - RT1 class II, locus DMa

Predicted to enable MHC class II protein complex binding activity. Predicted to be involved in peptide antigen assembly with MHC class II protein complex; positive regulation of germinal center formation; and positive regulation of humoral immune response. Predicted to act upstream of or within several processes, including antigen processing and presentation of exogenous peptide antigen via MHC class II; chaperone cofactor-dependent protein refolding; and positive thymic T cell selection. Predicted to be located in cell surface; late endosome; and lysosomal membrane. Predicted to be part of MHC class II protein complex. Orthologous to human HLA-DMA (major histocompatibility complex, class II, DM alpha). [provided by Alliance of Genome Resources, Apr 2022]