RT1-DMb - RT1 class II, locus DMb

Predicted to enable MHC class II protein complex binding activity. Predicted to be involved in peptide antigen assembly with MHC class II protein complex; positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; and positive regulation of T cell proliferation. Predicted to act upstream of or within antigen processing and presentation of exogenous peptide antigen via MHC class II and chaperone cofactor-dependent protein refolding. Predicted to be located in late endosome membrane; lysosomal membrane; and multivesicular body. Predicted to be integral component of membrane. Predicted to be part of MHC class II protein complex. Orthologous to human HLA-DMB (major histocompatibility complex, class II, DM beta). [provided by Alliance of Genome Resources, Apr 2022]