大鼠

Bace1 - beta-secretase 1

Alias:
Bace
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有肽酶活性。参与几个过程,包括对淀粉样β的细胞反应;对金属离子的细胞反应;以及检测与疼痛感知有关的机械刺激。位于几个细胞组件中,包括高尔基器;细胞质囊泡;和神经元细胞体。用于研究痴呆。阿尔茨海默病的生物标志物;感觉周围神经病变;和短暂脑缺血。这个基因的人类同源物与阿尔茨海默病有关。与人类BACE1(β-分泌酶1)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
9
24209 bp
55.81
21
1

Bace1 Genetics information (+)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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