人类

GSTA1 - Glutathione S-transferase Alpha 1

Alias:
GST2
GTH1
GSTA1-1
GST-epsilon
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个酶家族成员,该家族的功能是将谷胱甘肽添加到目标亲电化合物上,包括致癌物质、治疗药物、环境毒素和氧化应激产物。这一作用是这些化合物的解毒的重要步骤。这个酶亚家族在保护细胞免受活性氧物种和过氧化产物的影响方面具有特殊作用。这个基因的多态性影响个体代谢不同药物的能力。这个基因位于染色体6上一个类似基因和假基因的簇中。可选的剪接导致多个转录变异体。[由RefSeq,2016年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3
7
12446 bp
25.63
10
--
5
24

GSTA1 Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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