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中文大鼠
Irs2 - insulin receptor substrate 2
Alias:
4PS
IRS-2
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具有多种功能，包括14-3-3蛋白结合活性；胰岛素受体结合活性；和磷酸肌醇3-激酶结合活性。参与细胞对葡萄糖刺激的响应和胰岛素受体信号通路。预测是含有蛋白质的复合物的一部分。预测在细胞质和质膜中是活跃的。非酒精性脂肪肝病的生物标志物和骨质疏松症的生物标志物。该基因的人类同源物与2型糖尿病有关。与人类IRS2（胰岛素受体底物2）正交。[由基因组资源联盟，2022年4月提供]
Related ID：
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Irs2 Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
