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Hras - HRas proto-oncogene, GTPase

Alias:
HRAS1
c-H-ras
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够激活GTP酶活性;鸟苷核苷酸结合活性;和蛋白质C端结合活性。参与几个过程,包括细胞衰老;DNA复制的正调控;ERK1和ERK2级联的正调控。位于信号传导上游或正调控Ras蛋白内。位于细胞内膜界定的细胞器和质膜上。用于研究糖尿病性视网膜病变和肝癌。该基因的人类同源物与几种疾病有关,包括科斯特洛综合征;自症;癌(多种);表皮痣;和大型先天性黑色素痣。与人类HRAS(HRas原癌基因,GTP酶)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
5
5
9697 bp
21.30
15
9

Hras Genetics information (-)

mRatBN7.2

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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