Enables cAMP-dependent protein kinase activity. Involved in negative regulation of meiotic cell cycle; protein phosphorylation; and response to clozapine. Located in cytosol; nucleus; and perinuclear region of cytoplasm. Part of cAMP-dependent protein kinase complex. Biomarker of brain ischemia. Orthologous to human PRKACB (protein kinase cAMP-activated catalytic subunit beta). [provided by Alliance of Genome Resources, Apr 2022]