Enables phosphatidylinositol phospholipase C activity. Involved in several processes, including positive regulation of cell cycle G1/S phase transition; response to ATP; and response to magnesium ion. Located in membrane. Human ortholog(s) of this gene implicated in familial cold autoinflammatory syndrome 3. Orthologous to human PLCG2 (phospholipase C gamma 2). [provided by Alliance of Genome Resources, Apr 2022]