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中文大鼠
Irf3 - interferon regulatory factor 3
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具有多种功能，包括DNA结合转录激活因子活性，特异性为RNA聚合酶II；特异性结合启动子染色质活性；以及蛋白质同源二聚化活性。参与细胞对外源dsRNA的响应；正调节I-kappaB激酶/NF-kappaB信号通路；以及正调节细胞因子的产生。预测位于细胞质和线粒体中。预测在细胞核中活性。该基因的人类同源物与脑疾病有关。与人类IRF3（干扰素调节因子3）正交。[由基因组资源联盟，2022年4月提供]
Related ID：
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Irf3 Genetics information (+)
mRatBN7.2
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
