Nlrp12 - NLR family, pyrin domain containing 12

Predicted to be involved in several processes, including negative regulation of NF-kappaB transcription factor activity; negative regulation of macromolecule metabolic process; and regulation of signal transduction. Predicted to act upstream of or within several processes, including dendritic cell migration; positive regulation of MHC class I biosynthetic process; and regulation of intracellular signal transduction. Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in familial cold autoinflammatory syndrome 2. Orthologous to human NLRP12 (NLR family pyrin domain containing 12). [provided by Alliance of Genome Resources, Apr 2022]